unpleasantness

n.

煞风景的事，不愉快的事；芥蒂；

1. You ought to be prepared for some unpleasantness.
   你要做好思想准备，可能发生一些不愉快的情况。
2. I want to avoid any unpleasantness with the neighbours.
   我要避免与邻居有任何不快。
3. I had a slight unpleasantness with the manager.
   我和经理之间有过一点磨擦。

Unpleasantness
The unpleasantness of tonic pain is encoded by the insular cortex.
The unpleasantness of dyspnea is processed in the human anterior insula and amygdala
Autobiographical memory: Unpleasantness fades faster than pleasantness over time.
Effects of attention on the intensity and unpleasantness of thermal pain
Differential Effects on Pain Intensity and Unpleasantness of Two Meditation Practices
Narcotic Analgesia: Fentanyl Reduces the Intensity but Not the Unpleasantness of Painful Tooth Pulp Sensations
Induction of depressed mood disrupts emotion regulation neurocircuitry and enhances pain unpleasantness.
Comparison of verbal and visual analogue scales for measuring the intensity and unpleasantness of experimental pain.
Gracely R, Dubner R, McGrath PJ. Narcotic analgesic: fentanyl reduces the intensity but not the unpleasantness of painful tooth pulp...