dominant negative

释义

[医]显性负相；

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension.
Functional inactivation of genes by dominant negative mutations
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogen...
Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila.
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome.
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos.